RESEARCH GROUP LEADER: Dr. László V. Frenyó, DVM, PhD
CONTACT: frenyo.laszlo@univet.hu
RESEARCH GROUP MEMBERS:
Professors: Dr. László V. Frenyó, Dr. Tibor Bartha
Associate professor: Dr. Ágnes Sterczer
Assistant professor: Dr. Dávid Sándor Kiss
Assistant lecturer: Dr. Istán Tóth
Assistant research fellow: Gergely Jócsák
Assistants: Gréta Goszleth, Zsuzsanna Kinálné Szikora
PhD student: Dr. Zoltán Bárány
RESEARCH AREAS:
Focus of research:
immunological features of exotic animals
impact of epigenetic factors on function and development of the immunoendocrine system
epigenetic effects on the up/down-regulation of hormone receptor expression; effects on the immune system
role of microglia in the pathogenesis of hepatic encephalopathy
Recent results:
The group is relatively newly reorganized after a few years of silence. Our preliminary results indicate that exogenous disruptor molecules mimicking endogenous hormone effects interact with the immune system.
Available equipment:
PCR equipment
Nanodrop for RNA, DNA and protein measurements
ELISA plate reader for quantitative protein/enzyme/hormone/etc. measurements
thermostat and laminar box for investigations on cell cultures
full apparatus for Western blot studies and gel documentation for qualitative and semi-quantitative protein assays
animal house (for rodents and rabbit)
MEMBERSHIPS:
Hungarian Physiological Society (MÉT)
Hungarian Society of Animal Protection and Animal Welfare (MÁÁT)
Hungarian Neuroscience Society (MITT)
Research and Technological Innovation
LONG-TERM COLLABORATIONS:
University of Iowa, Iowa city, USA
Yale University, Connecticut, USA
University of Veterinary Medicine Hannover, Germany
Hohenheim University, Stuttgart, Germany
Semmelweis University, Hungary
University of Kaposvár, Hungary
Purdue University, Indiana, USA
GRANTS:
|
Funding source |
Project title and topic |
Amount (HUF) |
|
Research Faculty (Ministry of Human Capacities) |
Establishment of primary astrocyte culture suitable for the investigations of hepatic encephalopathy (2015) |
1.500.000 |
|
NKB 15991 |
Co-culture of rat endothelial cells and astrocytes – working out an in vitro model for hepatic encephalopathy |
735.000 |
|
Research Faculty (Ministry of Human Capacities) |
Examination of the glutaminase inhibiting effects of a non-specific phosphodiesterase inhibitor, theophyllin on an in vitro model of hepatic encephalopathy (2016) |
1.000.000 |
|
Research Faculty (Ministry of Human Capacities) |
Cytokine production in astrocytes as a result of oxidative stress (2016) |
1.000.000 |