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</html><description>NEW SYNTHETIC ROUTES TO BRIDGEHEAD N-HETEROCYCLES Research Plan 1.Introduction The pyrrolizidine-, indolizidine-, and quinolizidine-alkaloids (izidines) found in diverse species of the biosphere (fungi, arthropoda, amphibia, plants) exhibit versatile biological activities. Some of them are defending compounds of arthropoda, while others are very toxic, like alkyl-indolizidines isolated from the skin secretions of neotropical frogs. As potential</description></oembed>
