{"id":4474,"date":"2016-08-02T15:01:00","date_gmt":"2016-08-02T13:01:00","guid":{"rendered":"http:\/\/univet.hu\/egyetem\/munkatarsak\/pasztine-dr-gere-erzsebet\/"},"modified":"2025-02-06T20:27:43","modified_gmt":"2025-02-06T19:27:43","slug":"pasztine-dr-gere-erzsebet","status":"publish","type":"page","link":"https:\/\/univet.hu\/hu\/egyetem\/munkatarsak\/pasztine-dr-gere-erzsebet\/","title":{"rendered":"P\u00e1sztin\u00e9 dr. Gere Erzs\u00e9bet"},"content":{"rendered":"<p style=\"font-family: impact, sans-serif\" align=\"justify\">Bemutatkoz\u00e1s<\/p> <p><strong>Tanulm\u00e1nyok:<\/strong><\/p> <ul> <li>1995-2000 Szegedi Tudom\u00e1nyegyetem, Szeged \u2013 gy\u00f3gyszer\u00e9sz (M.Sc.)<\/li> <li>1995-2002 Szegedi Tudom\u00e1nyegyetem, Szeged \u2013 angol- magyar szakford\u00edt\u00f3 (M.Sc.)<\/li> <li>2009-2012 Szegedi Tudom\u00e1nyegyetem, Szeged- szakgy\u00f3gyszer\u00e9sz farmakol\u00f3giai szakir\u00e1ny<\/li> <li>2010-2013 Szent Istv\u00e1n Egyetem, \u00c1llatorvostudom\u00e1nyi Kar, Budapest \u2013 \u00e1llatorvosi tudom\u00e1nyok (Ph.D.)<\/li> <li>2018: Habilit\u00e1ci\u00f3, \u00c1llatorvostudom\u00e1nyi Egyetem, Budapest<\/li> <\/ul> <p><strong>Oktat\u00e1si tev\u00e9kenys\u00e9g r\u00e9szletez\u00e9se: <\/strong><\/p> <ul> <li>El\u0151ad\u00e1sok \u00e9s gyakorlatok tart\u00e1sa gy\u00f3gyszertani \u00e9s toxikol\u00f3giai t\u00e9mak\u00f6r\u00f6kben magyar \u00e9s angol nyelven<\/li> <li>Fakult\u00e1ci\u00f3k tart\u00e1sa sportfarmakol\u00f3gia, pszichofarmakol\u00f3gia, magisztr\u00e1lis gy\u00f3gyszerk\u00e9sz\u00edt\u00e9s \u00e9s feh\u00e9rjemodul\u00e1ci\u00f3 t\u00e9mak\u00f6r\u00f6kben magyar \u00e9s angol nyelven (tant\u00e1rgyfelel\u0151s- oktat\u00f3)<\/li> <li>Posztgradu\u00e1lis (PhD) kurzusok tart\u00e1sa: Eukari\u00f3ta sejtek teny\u00e9szt\u00e9se \u00e9s Redox \u00e1llapot \u00e9s oxidat\u00edv stressz a sejtek \u00e9let\u00e9ben<\/li> <\/ul> <p>&nbsp;<\/p> <p>20 befejezett TDK munka \u00e9s 1 v\u00e9gzett PhD hallgat\u00f3 (Dr. B\u00fas-Pomothy Judit) t\u00e9mavezet\u0151i ir\u00e1ny\u00edt\u00e1sa.<\/p> <ul> <li>Dr. Barna R\u00e9ka Fanni OTDK 2. helyezett \u00c1llat\u00e9lettan tagozat<\/li> <li>Dr. Czimmermann Eszter OTDK 3. helyezett \u00c1llat\u00e9lettan tagozat.<\/li> <li>Dr. Szombath Gergely OTDK 1. helyezett \u00c1llateg\u00e9szs\u00e9g\u00fcgyi tagozat<\/li> <\/ul> <p><strong>Tanulm\u00e1nyutak:<\/strong><\/p> <ul> <li>2002-2003 Michigani Egyetem, Ann Arbor, MI, USA <ul> <li>neurofarmakol\u00f3giai kutat\u00e1sok v\u00e9gz\u00e9se patk\u00e1ny striat\u00e1lis szeleteken<\/li> <\/ul> <\/li> <li>2014 Philipps Egyetem, Marburg, N\u00e9metorsz\u00e1g <ul> <li>matript\u00e1z inhibitorok szint\u00e9zise, enzimkinetikai vizsg\u00e1latok<\/li> <\/ul> <\/li> <\/ul> <p><strong>Tags\u00e1g tudom\u00e1nyos t\u00e1rsas\u00e1gokban:<\/strong><\/p> <p>2011- Magyar Mikrobiol\u00f3giai T\u00e1rsas\u00e1g<\/p> <p><strong>Elnyert d\u00edjak, kit\u00fcntet\u00e9sek:<\/strong><\/p> <ul> <li>2014 Erd\u0151s P\u00e1l Kutat\u00f3i \u00d6szt\u00f6nd\u00edj, Nemzeti Kiv\u00e1l\u00f3s\u00e1g program<\/li> <li>2015 OTKA posztdoktori \u00f6szt\u00f6nd\u00edj<\/li> <li>2015 Bolyai J\u00e1nos Kutat\u00f3i \u00f6szt\u00f6nd\u00edj \u2013 Magyar Tudom\u00e1nyos Akad\u00e9mia<\/li> <\/ul> <p><strong>Fontosabb kutat\u00e1si programok, elnyert p\u00e1ly\u00e1zatok:<\/strong><\/p> <ul> <li>2014-2015 KK-UK Matript\u00e1z inhibitorok hat\u00e9konys\u00e1g\u00e1nak vizsg\u00e1lata sert\u00e9s b\u00e9lh\u00e1msejteken, sert\u00e9sekben el\u0151fordul\u00f3 enter\u00e1lis \u00e9s hepatikus szab\u00e1lyoz\u00e1si zavarok <em>in vitro<\/em> jellemz\u00e9se<\/li> <li>2015-2020 OTKA 115685 Xenobiotikumok \u00e1ltal okozott b\u00e9lk\u00e1rosod\u00e1sok sert\u00e9sekben<\/li> <li>2016 KK-KF Preklinikai Gy\u00f3gyszer-fejleszt\u00e9si Kutat\u00f3csoport<\/li> <li>2017-2022 OTKA 124522 Probiotikumok, antioxid\u00e1nsok hat\u00e1sai gy\u00f3gyszerek, toxikus \u00e9s fert\u0151z\u0151 \u00e1gensek okozta sert\u00e9s h\u00e1msejt-k\u00e1rosod\u00e1sokban <em>in vitro<\/em><\/li> <\/ul> <hr align=\"center\" size=\"5\" width=\"60%\" \/> <p><span style=\"font-family: impact, sans-serif\">El\u0151rehalad\u00e1s<\/span><\/p> <table style=\"height: 127px;width: 812px\" width=\"811\"> <tbody> <tr style=\"height: 56px\"> <td style=\"width: 178px;text-align: center;height: 56px\">2010 &#8211; 2013<\/td> <td style=\"width: 618px;height: 56px\"> <p style=\"text-align: center\">PhD hallgat\u00f3<\/p> <\/td> <\/tr> <tr style=\"height: 24px\"> <td style=\"width: 178px;height: 24px;text-align: center\">2013 &#8211; 2014<\/td> <td style=\"width: 618px;height: 24px;text-align: center\">tansz\u00e9ki gy\u00f3gyszer\u00e9sz<\/td> <\/tr> <tr style=\"height: 24px\"> <td style=\"width: 178px;height: 24px;text-align: center\">2014 &#8211; 2019<\/td> <td style=\"width: 618px;height: 24px;text-align: center\">tudom\u00e1nyos munkat\u00e1rs<\/td> <\/tr> <tr style=\"height: 24px\"> <td style=\"width: 178px;height: 23px;text-align: center\">2019 &#8211;<\/td> <td style=\"width: 618px;height: 23px;text-align: center\">tudom\u00e1nyos f\u0151munkat\u00e1rs<\/td> <\/tr> <\/tbody> <\/table> <hr align=\"center\" size=\"5\" width=\"60%\" \/> <p><span style=\"font-family: impact, sans-serif\">Publik\u00e1ci\u00f3s lista (Top10)<\/span><\/p> <p style=\"text-align: center\">MTMT: <a href=\"https:\/\/m2.mtmt.hu\/gui2\/?type=authors&amp;mode=browse&amp;sel=authors10023380\">https:\/\/m2.mtmt.hu\/gui2\/?type=authors&amp;mode=browse&amp;sel=authors10023380<\/a><\/p> <hr align=\"center\" size=\"5\" width=\"60%\" \/> <table style=\"height: 279px;width: 113.544%\" width=\"1140\"> <tbody> <tr style=\"height: 86px\"> <td style=\"width: 36px;height: 86px;text-align: center\">1.<\/td> <td style=\"width: 1088px;height: 86px\">Gamba D, van Eijk N, L\u00e1nyi K, Monostory K, Steinmetzer T, Marosi A, R\u00e1cz A, Bajusz D, Kruhl D, B\u00f6ttcher-Friebertsh\u00e4user E, P\u00e1szti-Gere E. PK\/PD investigation of antiviral host matriptase\/TMPRSS2 inhibitors in cell models. Sci Rep. 2024 Jul 18;14(1):16621. doi: 10.1038\/s41598-024-67633-2.<\/td> <\/tr> <tr style=\"height: 54px\"> <td style=\"width: 36px;height: 54px;text-align: center\">2.<\/td> <td style=\"width: 1088px;height: 54px\">Maluck S, Bobrovsky R, Po\u00f3r M, Lange RW, Steinmetzer T, Jerzsele \u00c1, Adorj\u00e1n A, Bajusz D, R\u00e1cz A, P\u00e1szti-Gere E. In Vitro Evaluation of Antipseudomonal Activity and Safety Profile of Peptidomimetic Furin Inhibitors. Biomedicines. 2024 Sep 11;12(9):2075. doi: 10.3390\/biomedicines12092075.<\/td> <\/tr> <tr style=\"height: 54px\"> <td style=\"width: 36px;height: 54px;text-align: center\">3.<\/td> <td style=\"width: 1088px;height: 54px\">van Niekerk AA, Maluck S, Mag P, K\u0151v\u00e1g\u00f3 C, Kerek \u00c1, Jerzsele \u00c1, Steinmetzer T, P\u00e1szti-Gere E. Antiviral Drug Candidate Repositioning for <em>Streptococcus suis<\/em> Infection in Non-Tumorigenic Cell Models. Biomedicines. 2024 Apr 2;12(4):783. doi: 10.3390\/biomedicines12040783.<\/td> <\/tr> <tr style=\"height: 54px\"> <td style=\"width: 36px;height: 54px;text-align: center\">4.<\/td> <td style=\"width: 1088px;height: 54px\">L\u00e1nyi K, Monostory K, Steinmetzer T, Jerzsele \u00c1, P\u00e1szti-Gere E. In Vitro Pharmacokinetic Behavior of Antiviral 3-Amidinophenylalanine Derivatives in Rat, Dog and Monkey Hepatocytes. Biomedicines. 2023 Feb 23;11(3):682. doi: 10.3390\/biomedicines11030682.<\/td> <\/tr> <tr style=\"height: 31px\"> <td style=\"width: 36px;height: 31px;text-align: center\">5.<\/td> <td style=\"width: 1088px;height: 31px\">van Eijk N, Schmacke LC, Steinmetzer T, Pilgram O, Po\u00f3r M, P\u00e1szti-Gere E. In vitro testing of host-targeting small molecule antiviral matriptase\/TMPRSS2 inhibitors in 2D and 3D cell-based assays. Biomed Pharmacother. 2023 Dec;168:115761. doi: 10.1016\/j.biopha.2023.115761. Epub 2023 Oct 20.<\/td> <\/tr> <tr> <td style=\"width: 36px;text-align: center\">6.<\/td> <td style=\"width: 1088px\">Fedor Z, Szentkir\u00e1lyi-T\u00f3th A, Nagy G, Szimr\u00f3k Z, Varga E, P\u00e1szti A, P\u00e1szti Z, Jerzsele \u00c1, Pilgram O, Steinmetzer T, M\u00e1tis G, Neogr\u00e1dy Z, P\u00e1szti-Gere E. Interspecies Comparisons of the Effects of Potential Antiviral 3-Amidinophenylalanine Derivatives on Cytochrome P450 1A2 Isoenzyme. Vet Sci. 2022 Mar 23;9(4):156. doi: 10.3390\/vetsci9040156.<\/td> <\/tr> <tr> <td style=\"width: 36px;text-align: center\">7.<\/td> <td style=\"width: 1088px\">P\u00e1szti-Gere E, Szentkir\u00e1lyi-T\u00f3th A, Szab\u00f3 P, Steinmetzer T, Flisz\u00e1r-Ny\u00fal E, Po\u00f3r M. In vitro characterization of the furin inhibitor MI-1851: Albumin binding, interaction with cytochrome P450 enzymes and cytotoxicity. Biomed Pharmacother. 2022 Jul;151:113124. doi: 10.1016\/j.biopha.2022.113124. Epub 2022 May 17.<\/td> <\/tr> <tr> <td style=\"width: 36px;text-align: center\">8.<\/td> <td style=\"width: 1088px\">P\u00e1szti-Gere E, Szentkir\u00e1lyi A, Fedor Z, Nagy G, Szimr\u00f3k Z, P\u00e1szti Z, P\u00e1szti A, Pilgram O, Steinmetzer T, Bodn\u00e1rov\u00e1 S, Flisz\u00e1r-Ny\u00fal E, Po\u00f3r M. In vitro interaction of potential antiviral TMPRSS2 inhibitors with human serum albumin and cytochrome P 450 isoenzymes. Biomed Pharmacother. 2022 Feb;146:112513. doi: 10.1016\/j.biopha.2021.112513. Epub 2021 Dec 13.<\/td> <\/tr> <tr> <td style=\"width: 36px;text-align: center\">9.<\/td> <td style=\"width: 1088px\">Wohlert A, Palkovicsn\u00e9 P\u00e9zsa N, M\u00f3ritz AV, Jerzsele \u00c1, Farkas O, P\u00e1szti-Gere E. Luteolin and Chrysin Could Prevent <em>E. coli<\/em> Lipopolysaccharide-Ochratoxin A Combination-Caused Inflammation and Oxidative Stress in In Vitro Porcine Intestinal Model. Animals (Basel). 2022 Oct 13;12(20):2747. doi: 10.3390\/ani12202747.<\/td> <\/tr> <tr> <td style=\"width: 36px;text-align: center\">10.<\/td> <td style=\"width: 1088px\">P\u00e1szti-Gere E, Pomothy J, Jerzsele \u00c1, Pilgram O, Steinmetzer T. Exposure of human intestinal epithelial cells and primary human hepatocytes to trypsin-like serine protease inhibitors with potential antiviral effect. J Enzyme Inhib Med Chem. 2021 Dec;36(1):659-668. doi: 10.1080\/14756366.2021.1886093.<\/td> <\/tr> <\/tbody> <\/table> <p>&nbsp;<\/p> <p>(Friss\u00edtve: 2025. janu\u00e1r)<\/p>","protected":false},"excerpt":{"rendered":"<p>Bemutatkoz\u00e1s Tanulm\u00e1nyok: 1995-2000 Szegedi Tudom\u00e1nyegyetem, Szeged \u2013 gy\u00f3gyszer\u00e9sz (M.Sc.) 1995-2002 Szegedi Tudom\u00e1nyegyetem, Szeged \u2013 angol- magyar szakford\u00edt\u00f3 (M.Sc.) 2009-2012 Szegedi Tudom\u00e1nyegyetem, Szeged- szakgy\u00f3gyszer\u00e9sz farmakol\u00f3giai szakir\u00e1ny 2010-2013 Szent Istv\u00e1n Egyetem, \u00c1llatorvostudom\u00e1nyi Kar, Budapest \u2013 \u00e1llatorvosi tudom\u00e1nyok (Ph.D.) 2018: Habilit\u00e1ci\u00f3, \u00c1llatorvostudom\u00e1nyi Egyetem, Budapest Oktat\u00e1si tev\u00e9kenys\u00e9g r\u00e9szletez\u00e9se: El\u0151ad\u00e1sok \u00e9s gyakorlatok tart\u00e1sa gy\u00f3gyszertani \u00e9s toxikol\u00f3giai t\u00e9mak\u00f6r\u00f6kben magyar \u00e9s angol<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":858,"menu_order":211,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[56],"tags":[],"class_list":["post-4474","page","type-page","status-publish","hentry","category-munkatarsak"],"acf":[],"_links":{"self":[{"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/pages\/4474","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/comments?post=4474"}],"version-history":[{"count":3,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/pages\/4474\/revisions"}],"predecessor-version":[{"id":172929,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/pages\/4474\/revisions\/172929"}],"up":[{"embeddable":true,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/pages\/858"}],"wp:attachment":[{"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/media?parent=4474"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/categories?post=4474"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/univet.hu\/hu\/wp-json\/wp\/v2\/tags?post=4474"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}