{"id":11027,"date":"2016-03-01T11:33:00","date_gmt":"2016-03-01T10:33:00","guid":{"rendered":"https:\/\/univet.hu\/kat\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/"},"modified":"2016-03-01T11:33:00","modified_gmt":"2016-03-01T10:33:00","slug":"potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben","status":"publish","type":"page","link":"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/","title":{"rendered":"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model"},"content":{"rendered":"<p>Intestinal epithelial cells play important role against external noxious stimuli such as bacterial infections and mycotoxin-induced intestinal inflammation.<\/p> <p>The goal of this research study is to determine changes in integrity of intestinal barrier after treatment of the cells either with enteropathogens or with mycotoxins using IPEC-J2 cell line derived from neonatal, unsuckled piglet. Further aim of the research is to elucidate the barrier-reinforcing properties of probiotics or their metabolites, and certain antioxidants in case of xenobiotics-induced intestinal damage.<\/p> <p>During the experiments based on transepithelial electrical resistance and paracellular permeability measurements potential intestinal barrier protective compounds will be selected and assessed in-depth.<\/p>","protected":false},"excerpt":{"rendered":"<p>Intestinal epithelial cells play important role against external noxious stimuli such as bacterial infections and mycotoxin-induced intestinal inflammation. The goal of this research study is to determine changes in integrity of intestinal barrier after treatment of the cells either with enteropathogens or with mycotoxins using IPEC-J2 cell line derived from neonatal, unsuckled piglet. Further aim<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":873,"menu_order":154,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-11027","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.2 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model - University of Veterinary Medicine Budapest<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model - University of Veterinary Medicine Budapest\" \/>\n<meta property=\"og:description\" content=\"Intestinal epithelial cells play important role against external noxious stimuli such as bacterial infections and mycotoxin-induced intestinal inflammation. The goal of this research study is to determine changes in integrity of intestinal barrier after treatment of the cells either with enteropathogens or with mycotoxins using IPEC-J2 cell line derived from neonatal, unsuckled piglet. Further aim\" \/>\n<meta property=\"og:url\" content=\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/\" \/>\n<meta property=\"og:site_name\" content=\"University of Veterinary Medicine Budapest\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/\",\"url\":\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/\",\"name\":\"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model - University of Veterinary Medicine Budapest\",\"isPartOf\":{\"@id\":\"https:\/\/univet.hu\/kat\/#website\"},\"datePublished\":\"2016-03-01T10:33:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Kezd\u0151lap\",\"item\":\"https:\/\/univet.hu\/kat\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Topics\",\"item\":\"https:\/\/univet.hu\/kat\/en\/topics\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/univet.hu\/kat\/#website\",\"url\":\"https:\/\/univet.hu\/kat\/\",\"name\":\"Univet Katal\u00f3gus\",\"description\":\"Since 1787\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/univet.hu\/kat\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model - University of Veterinary Medicine Budapest","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/univet.hu\/kat\/en\/topics\/potencialisan-vedo-hatasu-anyagok-alkalmazhatosaga-xenobiotikumok-altal-karositott-belbarrier-epsegenek-fenntartasara-in-vitro-modellben\/","og_locale":"en_US","og_type":"article","og_title":"Applicability of xenobiotics and potentially protective agents on the intestinal barrier integrity using in vitro model - University of Veterinary Medicine Budapest","og_description":"Intestinal epithelial cells play important role against external noxious stimuli such as bacterial infections and mycotoxin-induced intestinal inflammation. 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