{"id":11071,"date":"2016-02-04T16:00:00","date_gmt":"2016-02-04T15:00:00","guid":{"rendered":"https:\/\/univet.hu\/kat\/topics\/epigenetic-studies-on-histone-deacetylase-inhibitors\/"},"modified":"2016-02-04T16:00:00","modified_gmt":"2016-02-04T15:00:00","slug":"epigenetic-studies-on-histone-deacetylase-inhibitors","status":"publish","type":"page","link":"https:\/\/univet.hu\/kat\/en\/topics\/epigenetic-studies-on-histone-deacetylase-inhibitors\/","title":{"rendered":"Epigenetic studies on histone deacetylase inhibitors"},"content":{"rendered":"<p>The widespreading intestinal and extraintestinal effects of butyrate are mostly based on the epigenetic regulation of gene expression by the inhibition of histone deacetylases (HDAC). In comparison with the already known in vitro HDAC inhibitory activity of butyrate, the main goal of this project is to study the in vivo effect of oral butyrate application on hepatic histone acetylation in chicken. Cooperation with Prof. Korinna Huber (University of Veterinary Medicine, Hannover, Germany).<\/p> <p>Staff:\u00a0Dr. G\u00e1bor M\u00e1tis, Dr. Zsuzsanna Neogr\u00e1dy<\/p>","protected":false},"excerpt":{"rendered":"<p>The widespreading intestinal and extraintestinal effects of butyrate are mostly based on the epigenetic regulation of gene expression by the inhibition of histone deacetylases (HDAC). In comparison with the already known in vitro HDAC inhibitory activity of butyrate, the main goal of this project is to study the in vivo effect of oral butyrate application<\/p>\n","protected":false},"author":0,"featured_media":0,"parent":873,"menu_order":154,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"categories":[],"tags":[],"class_list":["post-11071","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Epigenetic studies on histone deacetylase inhibitors - Univet Katal\u00f3gus<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/univet.hu\/kat\/en\/topics\/epigenetic-studies-on-histone-deacetylase-inhibitors\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Epigenetic studies on histone deacetylase inhibitors - Univet Katal\u00f3gus\" \/>\n<meta property=\"og:description\" content=\"The widespreading intestinal and extraintestinal effects of butyrate are mostly based on the epigenetic regulation of gene expression by the inhibition of histone deacetylases (HDAC). In comparison with the already known in vitro HDAC inhibitory activity of butyrate, the main goal of this project is to study the in vivo effect of oral butyrate application\" \/>\n<meta property=\"og:url\" content=\"https:\/\/univet.hu\/kat\/en\/topics\/epigenetic-studies-on-histone-deacetylase-inhibitors\/\" \/>\n<meta property=\"og:site_name\" content=\"Univet Katal\u00f3gus\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/epigenetic-studies-on-histone-deacetylase-inhibitors\\\/\",\"url\":\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/epigenetic-studies-on-histone-deacetylase-inhibitors\\\/\",\"name\":\"Epigenetic studies on histone deacetylase inhibitors - Univet Katal\u00f3gus\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/univet.hu\\\/kat\\\/#website\"},\"datePublished\":\"2016-02-04T15:00:00+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/epigenetic-studies-on-histone-deacetylase-inhibitors\\\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/epigenetic-studies-on-histone-deacetylase-inhibitors\\\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/epigenetic-studies-on-histone-deacetylase-inhibitors\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Kezd\u0151lap\",\"item\":\"https:\\\/\\\/univet.hu\\\/kat\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Topics\",\"item\":\"https:\\\/\\\/univet.hu\\\/kat\\\/en\\\/topics\\\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Epigenetic studies on histone deacetylase inhibitors\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/univet.hu\\\/kat\\\/#website\",\"url\":\"https:\\\/\\\/univet.hu\\\/kat\\\/\",\"name\":\"Univet Katal\u00f3gus\",\"description\":\"\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/univet.hu\\\/kat\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Epigenetic studies on histone deacetylase inhibitors - Univet Katal\u00f3gus","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/univet.hu\/kat\/en\/topics\/epigenetic-studies-on-histone-deacetylase-inhibitors\/","og_locale":"en_US","og_type":"article","og_title":"Epigenetic studies on histone deacetylase inhibitors - Univet Katal\u00f3gus","og_description":"The widespreading intestinal and extraintestinal effects of butyrate are mostly based on the epigenetic regulation of gene expression by the inhibition of histone deacetylases (HDAC). 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