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About Us Project Proposals NRDIO projects OTKA projects K 132833 – Comparative analysis of selected Pasteurellaceae bacterium species

K 132833 – Comparative analysis of selected Pasteurellaceae bacterium species

Total budget: 38.976.000 HUF

Project manager: Dr. László Fodor

Duration:

from 1st December 2019. to 30th November 2024.

 

Summary:

The Family Pasteurellaceae is very important from a veterinary point of view, since several bacterium species of this family can cause different and severe diseases in animals and sometimes in humans. Three bacterium species of Pasteurellaceae, Actinobacillus pleuropneumoniae, Histophilus somni and Mannheimia haemolytica are in the focus of the present research project. Our previous examinations have shown diversity of these bacterium species and we plan to analyse the structure of the whole genetic material of 30-50 A. pleuropneumoniae, H. somni and M. haemolytica isolates. We are going to examine the correlation between the genome structure of different A. pleuropneumoniae, H. somni and M. haemolytica strains and their host specificity, organ tropism, virulence, distribution, frequency, together with the geographical location, breed and husbandry technology of the sampled animals. The expected results can give a solid basis to evidence based prevention of the diseases caused by these bacteria and gaining healthy animal stocks.