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About Us Staff Farkas Orsolya

dr. Farkas Orsolya

Ph.D., habilitated
Department
Department of Pharmacology and Toxicology
Position
associate researcher
Location
Building R-S ground-floor

Studies

  • bioengineer MSc (2001, Budapest University of Technology and Economics)
  • PhD (2008, Budapest University of Technology and Economics)
  • habilitation (2018, University of Veterinary Medicine, Budapest)

Positions

  • 2001- Research Center for Natural Sciences (Hungarian Academy of Sciences) – Laboratory of Biooxidation (research area: in vitro techniques, photodynamic therapy, multivariate data analysis)
  • 2011- University of Veterinary Medicine, Budapest, Department of Pharmacology and Toxicology

Research area

  • in vitro models of inflammation and oxidative stress
  • role of polyphenols, plant extracts and probiotics in prevention inflammatory disease

Teaching activity

  • Veterinary pharmacology practicals
  • Veterinary toxicology
  • Introduction to cell culture technique (elective course)
  • Culture of eukaryotic cells (PhD course)

Advancement

2011-2012 researcher
2012 – 2019 research fellow
2018. habilitation
2019 – senior research fellow

TDK and thesis

  • 17 students
  • First prize in OTDK 2017 (Dóra Kovács, in section Veterinary Physiology) and OTDK 2023 (Fanni Somogyi, Dóra Kovács, in section Veterinary Physiology)
PhD-students
Dr. Karancsi Zita  2015
Pézsa Nikolett  2017
Dr. Kovács Dóra 2018
Dr. Móritz Alma 2021

Publications (Top10)

MTMT: https://m2.mtmt.hu/gui2/?type=authors&mode=browse&sel=authors10013542

1. Z. Karancsi, D. Kovacs, N. Pézsa; P. Gálfi, Á. Jerzsele, O. Farkas The Impact of Quercetin and Its Methylated Derivatives 3-o-Methylquercetin and Rhamnazin in Lipopolysaccharide-Induced Inflammation in Porcine Intestinal Cells Antioxidants 11: 7 Paper: 1265, 12 p. 2022
2. Kovács, D; Palkovicsné Pézsa, N.; Jerzsele, Á.; Süth, M.; Farkas, O. Protective Effects of Grape Seed Oligomeric Proanthocyanidins in IPEC-J2–Escherichia coli/Salmonella Typhimurium Co-Culture Antibiotics 11: 1 Paper: 110 202
3. Palkovicsné Pézsa, N.; Kovács, D.; Rácz, B.; Farkas, O. Effects of Bacillus licheniformis and Bacillus subtilis on Gut Barrier Function, Proinflammatory Response, ROS Production and Pathogen Inhibition Properties in IPEC-J2—Escherichia coli/Salmonella Typhimurium Co-Culture Microorganisms 10: 5 Paper: 936, 17 p. 2022
4. Palkovicsné, Pézsa N.; Kovács, D.; Gálfi, P.; Rácz, B.; Farkas, O. Effect of Enterococcus faecium NCIMB 10415 on Gut Barrier Function, Internal Redox State, Proinflammatory Response and Pathogen Inhibition Properties in Porcine Intestinal Epithelial Cells Nutrients 14: 7 Paper: 1486, 18 p. 202
5. Z. Karancsi, A.V. Móritz, N. Lewin, A. M. Veres, Á. Jerzsele, O. Farkas. Beneficial effect of fermented wheat germ extract in intestinal epithelial cells in case of lipopolysaccharide-evoked inflammation. Oxidative Medicine and Cellular Longevity. 2020
6.  D, Kovács; Z, Karancsi; O, Farkas; Á, Jerzsele Antioxidant activity of flavonoids in LPS-treated IPEC-J2 porcine intestinal epithelial cells and their antibacterial effect against bacteria of swine origin Antioxidants 9: 12 Paper: 1267 2020
7.  Farkas O, Karancsi Z, Kovacs D, Lubov B, Csiko G, Palocz O Effect of flavonoids on cytochrome P450 activity in porcine intestinal epithelial cells – in vitro interaction study Journal of Veterinary Pharmacology And Therapeutics 41:(1) pp. 142-143
8. Palocz O, Paszti-Gere E, Galfi P, Farkas O. Chlorogenic Acid Combined with Lactobacillus plantarum 2142 Reduced LPS-Induced Intestinal Inflammation and Oxidative Stress in IPEC-J2 Cells. Plos One 11:(11) Paper e0166642.
9. Farkas O, Palócz O, Pászti-Gere E, Gálfi P Polymethoxyflavone apigenin-trimethylether suppresses LPS-induced inflammatory response in non-transformed porcine intestinal cell line IPEC-J2 Oxidative Medicine and Cellular Longevity, Paper 673847
10.  Farkas O., G. Mátis, E. Pászti-Gere, O. Palócz, A. Kulcsár, J. Petrilla, Gy. Csikó, Zs. Neogrády, P. Gálfi Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in LPS-triggered inflammation: comparison of IPEC-J2 and primary hepatocyte mono-cultures with a porcine enterohepatic co-culture system Journal of Animal Science 92:(9), 3835-3845

 

(Updated: April 2023)