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Education Courses Veterinary biochemistry I

Veterinary biochemistry I

Language
English
Nature
mandatory
Method of evaluation
practical grade
Year in the curriculum
2
Semester in the curriculum
1
Credits
5
Lectures
45
Practical lessons
15
Specialization
veterinary (English)
Documents
Documents
Allow for
  • Vet EN

Course description

Homeostasis in the animal organism, transport processes across the biological membrane, characterization and regulation of the enzymatic reactions. Basic knowledge of the molecular biology.

 

Lectures theme

5-10. group

Date Topic Lecturer
11 September Introduction. Internal environment, homeostasis. Isovolaemia, isotonia, isoionia. Isohydria, buffer systems. (2 h) Dr. Neogrády Zsuzsanna
12 September Structure of the biological membranes. (1 h) Dr. Neogrády Zsuzsanna
18 September Transport across the biological membranes. (2 h) Dr. Neogrády Zsuzsanna
19 September Classification and structure of the proteinogenic amino acids. The peptide bond. (1 h) Dr. Neogrády Zsuzsanna
25 September General characterization and structure of proteins. Denaturation and renaturation of proteins. Classification of proteins. (2 h) Dr. Neogrády Zsuzsanna
26 September Structural proteins: collagen, elastin, keratin. (1 h) Dr. Neogrády Zsuzsanna
2 October Characterization of enzymes. Mechanism of enzyme action. Reversibility of enzymatic reactions. Factors influencing the velocity of enzymatic reactions. The regulation of the enzyme activity. (2 h) Dr. Neogrády Zsuzsanna
3 October The inhibition of the enzyme activity. Nomenclature, classification and cellular localization of enzymes. (1 h) Dr. Neogrády Zsuzsanna
9 October Structure of nucleotides. De novo synthesis of purine nucleotides. (2 h)  Dr. Orbán Kata
10 October Degradation of purine nucleotides. (1 h) Dr. Orbán Kata
16 October De novo synthesis and degradation of pyrimidine nucleotides. Salvage pathways of nucleotide metabolism (resynthesis of nucleotides). Metabolism of deoxyribonucleotides. (2 h) Dr. Orbán Kata
17 October The structure and function of DNA. (1 h) Dr. Orbán Kata
23 October Replication of DNA in prokaryotes and eukaryotes. Mutations, repair mechanisms. (2 h) Dr. Neogrády Zsuzsanna
24 October The structure of the transcription unit in prokaryotes and eukaryotes. Transcription and its regulation in prokaryotes. (1 h) Dr. Neogrády Zsuzsanna
30 October Transcription and its regulation in eukaryotes: gene expression, epigenetic regulatory mechanisms. (2 h) Dr. Neogrády Zsuzsanna
31 October Structure of the ribosomes. Activation of the amino acids. The steps of the translation in eukaryotes. (1 h) Dr. Neogrády Zsuzsanna
6 November The steps of the translation in prokaryotes. The regulation and energy balance of the translation. Posttranslational modifications of proteins. Recombinant DNA technology and biotechnology I. (2 h) Dr. Neogrády Zsuzsanna
7 November Recombinant DNA technology and biotechnology II. (1 h) Dr. Neogrády Zsuzsanna
13 November General introduction to the intermediary metabolism. Biological oxidation. Conservation of metabolic energy in the cell: high energy phosphates. Metabolism of creatine. (2 h) Dr. Neogrády Zsuzsanna
14 November Chemistry of carbohydrates: role, classification: monosaccharides, oligosaccharides, homo- and heteropolysaccharides. Cori cycle. (1 h) Dr. Neogrády Zsuzsanna
20 November Glycogen metabolism: glycogenolysis and glycogenesis. The glucagon and insulin signalling pathways. (2 h) Dr. Neogrády Zsuzsanna
21 November Glycolysis and gluconeogenesis: steps. (1 h) Dr. Neogrády Zsuzsanna
27 November Glycolysis and gluconeogenesis: regulation. Glycerol phosphate shuttle. Pasteur effect. The oxidation of pyruvate to acetyl CoA. (2 h) Dr. Neogrády Zsuzsanna
28 November The citric acid cycle. (1 h) Dr. Neogrády Zsuzsanna
4 December The respiratory chain and the oxidative phosphorylation. (2 h) Dr. Neogrády Zsuzsanna
5 December The pentose phosphate pathway. (1 h) Dr. Neogrády Zsuzsanna
11 December Blood sugar level and its regulation. (2 h) Dr. Mackei Máté
12 December Metabolism of fructose and galactose. (1 h) Dr. Mackei Máté

*The lecture of October 23rd (national holiday) will be held on another day.

1-4. group

Date Topic Lecturer
12 September Introduction. Internal environment, homeostasis. Isovolaemia, isotonia, isoionia. Isohydria, buffer systems. Structure of the biological membranes. (1+2 h) Dr. Neogrády Zsuzsanna
19 September Transport across the biological membranes. Classification and structure of the proteinogenic amino acids. The peptide bond. (1+2 h) Dr. Neogrády Zsuzsanna
26 September General characterization and structure of proteins. Denaturation and renaturation of proteins. Classification of proteins. Structural proteins: collagen, elastin, keratin. (1+2 h) Dr. Neogrády Zsuzsanna
3 October Characterization of enzymes. Mechanism of enzyme action. Reversibility of enzymatic reactions. Factors influencing the velocity of enzymatic reactions. The regulation of the enzyme activity. The inhibition of the enzyme activity. Nomenclature, classification and cellular localization of enzymes. (1+2 h) Dr. Neogrády Zsuzsanna
10 October Structure of nucleotides. De novo synthesis and degradation of purine nucleotides. (1+2 h) Dr. Orbán Kata
17 October De novo synthesis and degradation of pyrimidine nucleotides. Salvage pathways of nucleotide metabolism (resynthesis of nucleotides). Metabolism of deoxyribonucleotides. The structure and function of DNA. (1+2 h) Dr. Orbán Kata
24 October Replication of DNA in prokaryotes and eukaryotes. Mutations, repair mechanisms. The structure of the transcription unit in prokaryotes and eukaryotes. Transcription and its regulation in prokaryotes. (1+2 h) Dr. Neogrády Zsuzsanna
31 October Transcription and its regulation in eukaryotes: gene expression, epigenetic regulatory mechanisms. Structure of the ribosomes. Activation of the amino acids. The steps of the translation in eukaryotes. (2 h) Dr. Neogrády Zsuzsanna
7 November The steps of the translation in prokaryotes. The regulation and energy balance of the translation. Posttranslational modifications of proteins. Recombinant DNA technology and biotechnology. (1+2 h) Dr. Neogrády Zsuzsanna
14 November General introduction to the intermediary metabolism. Biological oxidation. Conservation of metabolic energy in the cell: high energy phosphates. Metabolism of creatine. Chemistry of carbohydrates: role, classification: monosaccharides, oligosaccharides, homo- and heteropolysaccharides. Cori cycle. (1+2 h) Dr. Neogrády Zsuzsanna
21 November Glycogen metabolism: glycogenolysis and glycogenesis. The glucagon and insulin signalling pathways. Glycolysis and gluconeogenesis: steps. (1+2 h) Dr. Neogrády Zsuzsanna
28 November Glycolysis and gluconeogenesis: regulation. Glycerol phosphate shuttle. Pasteur effect. The oxidation of pyruvate to acetyl CoA. The citric acid cycle. (1+2 h) Dr. Neogrády Zsuzsanna
5 December The respiratory chain and the oxidative phosphorylation. The pentose phosphate pathway. (1+2 h) Dr. Neogrády Zsuzsanna
12 December Blood sugar level and its regulation. Metabolism of fructose and galactose. (1+2 h) Dr. Mackei Máté

 

Practical lessons theme

Students are hereby informed that the order and dates of the laboratory practicals in Veterinary Biochemistry 1. are as follows:

Laboratory practical Subject Date Group
I. Blood plasma 23-27 September
30 September -4 October
2,4,6,8,10 1,3,5,7,9
II. Proteins 7-11 October
14-18 October
2,4,6,8,10 1,3,5,7,9
NO PRACTICAL LESSONS 21-25 October
III. General properties of enzymes 28-31 October
4-8 November
2,4,6,8,10 1,3,5,7,9
IV. Digestive enzymes 11-15 November
18-22 November
2,4,6,8,10 1,3,5,7,9
V. Nucleic acids 25-29 November

2-5 December

2,4,6,8,10 1,3,5,7,9

Make-up practicals:    Practicals III-V.

9th Dec (Monday), staring is possible between 1200 – 1400 o’clock.

Practicals I., II.

10th Dec (Tuesday), staring is possible between 1200 – 1400 o’clock.

Dr. Orbán Kata, professor assistant (E-mail: Orban.Kata@univet.hu) is responsible for the biochemical labs in English. For lab change request and further information please contact: Orban.Kata@univet.hu)

Evaluation description

Students are hereby informed that the prevalent qualification system and requirements in subject “Veterinary Biochemistry 1.” for the fall semester of the academic year 2019/2020 are as follows:

  • Regular visiting of the lectures (no more than 3 unjustified absences can be accepted)
  • Successful performance of all laboratory practicals
  • Completion of 60% of the maximal scores in the laboratory practicals
  • Completion of 60% of the maximal scores on the written midterm test

The date of the midterm test: 13th November 2019 at 715 am. in the „Kemény Armand” lecture hall.

Retake: 4th December 2019 at 715 am. in the „Kemény Armand” lecture hall.

Extra retake (from whole Biochemistry I): 13th December 2019 at 715 am. in the Kemény Armand lecture hall

51 – 55 points: excellent (5)
45 – 50 points: good (4)
40 – 44 points: medium (3)
33 – 39 points:  satisfactory (2)

Consultation possibility after registration: Dr. Kata Orbán, Tuesday, 1600-1800
(E-mail: Orban.Kata@univet.hu)

The complete qualification system of the subject can be downloaded from the webpage of the University https://univet.hu/en/biochemvet/