Course description

Intermediary metabolism: carbohydrates, amino acids, lipids. Biochemistry of different organs. Biochemistry of ruminants. Role of vitamins in the intermediary metabolism. Special focus on the veterinary clinical aspects of Biochemistry and the molecular basis of metabolic diseases.

Important note: All the PPT presentations are available on the Moodle page of the subject.

 

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Lectures theme

Students are hereby informed that the topics of the Biochemistry II. lectures in the spring semester of the academic year 2024/2025 are the followings:

 

Week	Topic	Lecturer
1.	Amino acid metabolism: essential amino acids, transamination, oxidative deamination. Detoxification of ammonia: urea cycle, alternative pathways.	Dr. Mackei Máté
2.	Decarboxylation of amino acids, biogenic amines. Glutathione, carnosine, anserine. Structure and function of hemoglobin. Porphyrine metabolism: synthesis of hemoglobin.	Dr. Mackei Máté
3.	Degradation of hemoglobin. Myoglobin, catalase, peroxidase, cytochromes. Iron metabolism. Synthesis of purine nucleotides.	Dr. Mátis Gábor**
4.	Degradation of purine nucleotides. Synthesis and degradation of pyrimidine nucleotides. Synthesis of deoxyribonucleotides. Resynthesis of nucleotides.	Dr. Mátis Gábor**
5.	Role and chemical structure of fats. Absorption and transport of fats. The lipolysis. Degradation of fatty acids: beta-oxidation of even-carbon, odd-carbon and unsaturated fatty acids.	Dr. Mackei Máté
6.	Ketogenesis, ketolysis. Biochemical background of ketosis. Synthesis of even-carbon, odd-carbon and unsaturated fatty acids.	Dr. Mackei Máté
7.	Lipogenesis. Steroids: structure and function of cholesterol. Synthesis of cholesterol. The metabolism of bile acids and steroid hormones.	Dr. Mackei Máté
8.	Carbohydrate metabolism of ruminants: degradation of dietary carbohydrates, production of the volatile fatty acids. Absorption and metabolism of the volatile fatty acids in the ruminants’ tissues. Metabolism of nitrogen-containing compounds in ruminants.	Dr. Mackei Máté
9.	Lipid metabolism of ruminants. Ketosis of the ruminants. Biochemistry of milk production. Role of the liver: intermediary metabolism, secretion.	Dr. Mackei Máté / Dr. Kemény Ágnes
10.	Detoxification funtion of the liver: synthesis, oxidation, reduction, hydrolysis, conjugation. Biochemistry of muscle, brain, adipose tissue and kidney Vitamins in general. Biochemistry of retinol (vitamin A).	Dr. Kemény Ágnes
11.	EASTER HOLIDAY, NO LECTURES
12.	Biochemistry of calcipherol (vitamin D), tocopherol (vitamin E) and phylloquinon (vitamin K).	Dr. Kemény Ágnes / Dr. Mackei Máté
13.*	Biochemistry of essential fatty acids, thiamine (vitamin B1), riboflavin (vitamin B2) and niacinamide (vitamin B3).	Dr. Mackei Máté
14.	Biochemistry of pantothenic acid (vitamin B5), pyridoxine (vitamin B6), biotin (vitamin B7) and folic acid (vitamin B9).	Dr. Mackei Máté
15.	Biochemistry of cobalamin (vitamin B12), ascorbic acid (vitamin C) and lipotropic factors.	Dr. Mackei Máté

*1 May is state holiday, the lecture will be held online.

Practical lessons theme

Spring semester, academic year 2024/2025

BIOCHEMISTRY II. in English

Students are hereby informed that the order and dates of the laboratory practicals in Biochemistry II. are as follows:

 

Lab No	Subject	Date	Groups
VI.	Blood sugar level and its regulation (online)	3-7 February 10-14 February	2,4,6,8,10 1,3,5,7,9
VII.	Biological oxidation	17-21. February 24-28 February	2,4,6,8,10 1,3,5,7,9
VIII.	Hemoglobin	3-7 March 10-14 March	2,4,6,8,10 1,3,5,7,9
IX.	Lipids	17-21 March 24-28 March	2,4,6,8,10 1,3,5,7,9
X.	Vitamins	31 March – 4. April 7-11. April	2,4,6,8,10 1,3,5,7,9
	EASTERN HOLIDAY NO PRACTICAL	14-18 April
	Additional practicals	5-9. May

 

Additional practicals:

Labs IX. – X.: 5 May, start: 12⁰⁰ – 15⁰⁰

Labs VI. – VIII.: 6 May, start: 12⁰⁰ – 15⁰⁰

 

Dr. Júlia Vörösházi (E-mail: Voroshazi.Julia@univet.hu) is responsible for the biochemical practicals in English.

For lab change request and further information, please contact: Voroshazi.Julia@univet.hu

Evaluation description

Spring semester, academic year 2024/2025

BIOCHEMISTRY II. in English

Students will be hereby informed that the prevalent qualification system and requirements in subject Biochemistry II. for the spring semester are as follows:

• Regular visiting of the lectures (no more than 3 unjustified absences can be accepted)
• Successful performance of all laboratory courses
• Completion of 60% of the maximal scores in the laboratory courses
• Completion of 60% of the maximal scores on the written midterm test

 

The complete qualification system of the subject can be downloaded from the webpage of the Department.

 

The date of the midterm test: 2 April 2025 at 7¹⁵.

Retake of the midterm: 30 April 2025 at 7¹⁵.

Extra retake (from whole Biochemistry II): 16 May 2025 at 7¹⁵.

The competition in Biochemistry will be held on: 9 May 2025, 15¹⁵ – 18⁰⁰

Consultation possibility after registration: E-mail: Mackei.Mate@univet.hu