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About Us Staff Farkas Orsolya

Farkas Orsolya

Name

dr. Farkas Orsolya

Degree
Ph.D., habilitated
Department
Department of Pharmacology and Toxicology
Position: associate researcher
Location
Building R-S ground-floor

Studies

  • bioengineer MSc (2001, Budapest University of Technology and Economics)
  • PhD (2008, Budapest University of Technology and Economics)
  • habilitation (2018, University of Veterinary Medicine, Budapest)

Positions

  • 2001- Research Center for Natural Sciences (Hungarian Academy of Sciences) – Laboratory of Biooxidation (research area: in vitro techniques, photodynamic therapy, multivariate data analysis)
  • 2011- University of Veterinary Medicine, Budapest, Department of Pharmacology and Toxicology

Research area

  • in vitro models of inflammation and oxidative stress
  • role of polyphenols, plant extracts and probiotics in prevention inflammatory disease

Teaching activity

  • Veterinary pharmacology practicals
  • Veterinary toxicology
  • Introduction to cell culture technique (elective course)
  • Culture of eukaryotic cells (PhD course)

Advancement

2011-2012 researcher
2012 – 2019 research fellow
2018. habilitation
2019 – senior research fellow

TDK and thesis

  • 17 students
  • First prize in OTDK 2017 (Dóra Kovács, in section Veterinary Physiology)
PhD-students
Dr. Karancsi Zita  2015
Pézsa Nikolett  2017
Dr. Kovács Dóra 2018

Publications

1.  Z. Karancsi, A.V. Móritz, N. Lewin, A. M. Veres, Á. Jerzsele, O. Farkas. Beneficial effect of fermented wheat germ extract in intestinal epithelial cells in case of lipopolysaccharide-evoked inflammation. Oxidative Medicine and Cellular Longevity. 2020 In press
2.  Farkas O, Karancsi Z, Kovacs D, Lubov B, Csiko G, Palocz O Effect of flavonoids on cytochrome P450 activity in porcine intestinal epithelial cells – in vitro interaction study Journal of Veterinary Pharmacology And Therapeutics 41:(1) pp. 142-143.
3.  Palocz O, Paszti-Gere E, Galfi P, Farkas O. Chlorogenic Acid Combined with Lactobacillus plantarum 2142 Reduced LPS-Induced Intestinal Inflammation and Oxidative Stress in IPEC-J2 Cells. Plos One 11:(11) Paper e0166642.
4.  Farkas O, Palócz O, Pászti-Gere E, Gálfi P Polymethoxyflavone apigenin-trimethylether suppresses LPS-induced inflammatory response in non-transformed porcine intestinal cell line IPEC-J2 Oxidative Medicine and Cellular Longevity, Paper 673847
5.  Farkas O., G. Mátis, E. Pászti-Gere, O. Palócz, A. Kulcsár, J. Petrilla, Gy. Csikó, Zs. Neogrády, P. Gálfi Effects of Lactobacillus plantarum 2142 and sodium n-butyrate in LPS-triggered inflammation: comparison of IPEC-J2 and primary hepatocyte mono-cultures with a porcine enterohepatic co-culture system Journal of Animal Science 92:(9), 3835-3845
6.  E. Paszti-Gere, G. Matis, O. Farkas, A. Kulcsar, O .Palocz, Gy Csiko, Zs. Neogrady, P. Galfi The effects of intestinal LPS exposure on inflammatory responses in a porcine enterohepatic co-culture system Inflammation 37:(1), 247-260
7.  Paszti-Gere E., Szeker K., Csibrik-Nemeth E., Csizinszky R., Marosi A., Palocz O., Farkas O., Galfi P. Metabolites of Lactobacillus plantarum 2142 Prevent Oxidative Stress-Induced Overexpression of Proinflammatory Cytokines in IPEC-J2 Cell Line Inflammation 35:(4), 1487-1499
8.  Jakus J., Farkas O. Photosensitizers and antioxidants: a way to new drugs? Photochem. Photobiol. Sci. 4, 694-968.
9.  Farkas O., Jakus J., Héberger K. Quantitative structure-antioxidant activity relationships of flavonoid compounds Molecules 9, 1079-1088
10.

 

(Updated: November 2020)