The effect of drugs (good and bad) is basically determined by the disposition within the body, i.e. the extent of distribution in biological media and elimination from the biological spaces. From pharmacokinetic point of view, there is wide diversity in the case of some species. This may be important in the development of beneficial and harmful effects of drugs in different animal species. For food-producing species other important aspect is that the pharmacokinetic effects may alter the clearance of drugs from products with animal origin intended for human consumption. The subject is designed to provide advanced and detailed knowledge to the topic, thus promoting the practice more effective and side effect-free use of medicines, and encourage the production of residue-free food.
|Date and time||Topics|
|Introduction, basic knowledge on pharmacokinetics and drug residues. The effects of genetics, age and health on the drug disposition in living organisms. Drug interactions. Statistical analysis on pharmacokinetics and drug elimination.|
|06.10.2022||Test methods prescribed for PK and drug residue examinations.
Testing methods of drug-metabolism (in vivo, in vitro).
|13.10.2022||The role of dose form (guest lecturer)
Variations in pharmacokinetics and drug metabolism in different animal species.
|Consultation||Upon personal request, the date and time must be set in advance.|
The time of the lectures will be finalized in consultation with the students.
Practical lessons theme
There are no practical in this course.
Attendance on lectures is obligatory, however student may miss max. 30% of lectures (one occasion), if it is indicated (e.g. illness, official program of university).
There is an online written examination at the end of course. When retake of examination is necessary, the general education rules of the campus should be considered.
Time will be determined later.