University of Veterinary Medicine Budapest

Course description

During Veterinary Pharmacology 2, students learn the theoretical and practical aspects of the usage of etiotropic drugs involving antimicrobial, antiparasitic and antineoplastic agents. Similarly to the first semester, we aim to develop students’ first day skills of drug use and educate pharmacology based on the relevant scientific literature supplemented with ethical, legal and public health aspects. Significant part of the course is dedicated to the pharmacology of antibacterial agents, where strong emphasis is put on the prudent use of these drugs due to the spread of antimicrobial resistance in both human and veterinary medicine. Furthermore, during practicals, students learn to calculate drug doses to be administered for both individual and mass treatment, and they perform and evaluate a complex pharmacokinetic investigation on broiler chickens.

Lectures theme

TOPICS OF LECTURES – VETERINARY PHARMACOLOGY

Academic year 2020/2021, 2^nd Semester

Budapest, 26th of January 2021

Ákos Jerzsele DVM, Ph.D
Head of Department, Associate Professor

Practical lessons theme

2^nd Semester 2020/2021.

Instructors

Budapest, 26th of January 2021

Ákos Jerzsele DVM, Ph.D
Head of Department, Associate Professor

Evaluation description

*Topic of the small tests and midterms

Small test1: First two practicals (Fluid therapy, Posology, Pharmacokinetics)

Small test2: Third, fourth and fifth practical (Inflammation, respiratory, cardiovascular pharmacology, hormones)

Small test3: Sixth, ninth, tenth practical (Reduction of AB usage, AB alternatives, disinfectants, AB usage Ru, Eq, Su, poultry)

All small tests can include dose calculations.

Midterm1: Antibiotics – Lectures 1-12 (Including quinolones)

Midterm2: Polypeptides, rifamycins, glycopeptides, sulphonamides and diaminopyrimidines, Anthelmintics I, II, Ectoparasiticids I, II – Lectures 13-14 and 17-22

“All small tests are obligatory and can be done only once (there will be no retake option). At least 60% should be achieved as an average of the three small tests. In case of not achieving 60%, a final retake test will be provided at the end of the semester covering all practical topics of the semester. If this is also failed, the student cannot get signature and cannot sign up for the exam.

Both midterms are obligatory, and one retake option will be provided for each. At least 60% should be achieved on both midterms for the signature. In case someone fails or misses any of the midterms, a final retake midterm should be written at the end of the semester, covering topics of both midterms. If this is also failed, the student cannot get signature and cannot sign up for the final exam. The midterm retakes can be taken by those, who passed the first occasion but would like to improve their result, however, the second result will count anyway, even if it is worse.

On the midterms’ weeks, there are no practicals.

The written exam is obligatory (unless someone achieves the 90% exemption). There are no choice limits, however, after 3 written exams, one option is lost from the oral exam. The oral exam can only be taken after successfully passing the written part. The written exam is successful in case of achieving at least 60%. The written exam covers practical topics of both semesters.

Final exam, written part:

25^th May (Tuesday)

31^st May (Monday)

7^th June (Monday)

14^th June (Monday)

21^st June (Monday)

28^th June (Monday)

On the oral exam, two topics must be discussed by students and each of them must be known on an acceptable level. The oral exam covers lecture topics of both semesters. Depending on the epidemiological situation, the oral exam will be held personally or via Microsoft Teams. Dates and further details will be announced later during the semester.

Small tests, midterms and the final exam will be written in the Moodle system. Their exact structure will be announced later during the semester.

In case of general questions about education, please contact dr. Dóra Kovács (kovacs.dora@univet.hu).

Budapest, 26th of January 2021

Ákos Jerzsele DVM, Ph.D
Head of Department, Associate Professor

Exam information

TOPICS OF THE PHARMACOLOGY EXAM
ACADEMIC YEAR 2020/2021

1. Mechanism of action of drugs: receptor- and non-receptor-mediated drug effects
2. Quantitative correlations of drug-receptor interactions, dissociation constant, quantal dose-response curve, efficacy, potency, therapeutic definitions, agonists, antagonists
3. Drug toxicity, drug side effects
4. Drug interactions and incompatibility
5. Factors influencing drug actions
6. Pharmacokinetics (absorption, distribution)
7. Pharmacokinetics (metabolism, elimination)
8. Pharmacokinetic calculations, principles of pharmacotherapy (bioavailability, loading dose, maintenance dose)
9. Parasympathomimetic and parasympatholytic agents
10. Sympathomimetics and sympatholytic agents
11. Neuroleptics (major tranquilizers)
12. Sedato-hypnotics
13. Opioids
14. Inhalational anaesthetics
15. Injectable anaesthetics
16. Anticonvulsants
17. Antidepressants and behaviour modifying agents
18. Peripheral muscle relaxants, spasmolytic agents
19. Local anaesthetics
20. Cardiotonics: Digitalis glycosides and phosphodiesterase inhibitors
21. ACE-inhibitors, angiotensin-receptor antagonists, vasodilators
22. Antiarrhythmic agents
23. Pharmacology of the respiratory tract
24. Emetics, antiemetics, prokinetic agents
25. Laxatives, antidiarrheals, appetite stimulants
26. Antiulcer agents and liver protectants
27. Diuretics
28. Pharmacology of the hypothalamus and hypophysis hormones
29. Insulin and other antidiabetics
30. Adrenocortical hormones, drugs for treatment of Cushing-disease and Addison-disease
31. Thyroid hormones, drugs for treatment of hypothyroidism and hyperthyroidism
32. Pharmacology of the drugs influencing sexual function 1. (GnRH and its analogues, gonadotropins, prostaglandins)
33. Pharmacology of the drugs influencing sexual function 2. (progestagens, oestrogens, androgens)
34. Uterus muscle stimulants and relaxants
35. Pharmacology of anaemia (iron, erythropoietin and derivative)
36. Antihistamines, leukotriene-receptor antagonists, Janus-kinase inhibitor, monoclonal antibodies in the veterinary medicine
37. Nonsteroidal anti-inflammatory agents
38. Glucocorticoids
39. Pharmacology of immunosuppression
40. Pharmacological basis of chemotherapy
41. Disinfectants
42. Penicillins and beta-lactamase inhibitors
43. Cefalosporins, monobactams and carbapenems
44. Aminoglycosides
45. Tetracyclines
46. Macrolides
47. Phenicols, lincosamides and pleuromutilins
48. Polypeptides and other antibiotics (glycopeptides, rifamycins)
49. Sulphonamides and diaminopyrimidines
50. Fluoroquinolones
51. Anticoccidial agents
52. Anti-protozoal agents (except coccidiosis)
53. Anthelmintics I. (benzimidazoles, imidazothiazoles, tetrahydropyrimidines)
54. Anthelmintics II. (salicylanilides, substituted phenols, isoquinolines, clorsulon, monepantel)
55. Endectocides (macrocyclic lactones)
56. Drugs against ectoparasites (except endectocides)
57. Antifungal agents
58. Antiviral agents
59. Antineoplastic agents

Budapest, 1th of February 2021

Ákos Jerzsele DVM, Ph.D
Head of Department, Associate Professor