RESEARCH GROUP LEADERS: Dr. Ferenc MANCZUR PhD, associate professor
CONTACT: [Click to see email]
MEMBERS:
1) Dr. Zsófia ARADI
2) Dr. Éva BALOGH
3) Dr. Márton BALOGH
4) Dr. Zsolt BECKER
5) Dr. Márton BOROS
6) Dr. Zoltán DUDÁS GYÖRKI
7) Dr. Fruzsina FALUS
8) Dr. Nóra GULYÁS
9) Dr. Fanni HÉTHÁRSI
10) Dr. Csaba HETYEY
11) Dr. Tünde KANYORSZKY
12) Dr. Gergely KISS
13) Dr. Ákos MÁTHÉ
14) Dr. Borbála MÓZES
15) Dr. Kinga PÁPA
16) Dr. Roland PSÁDER
17) Dr. Ágnes STERCZER
18) Dr. Viktória SUBA
19) Dr. Korinna SZABÓ
20) Dr. Noémi TARPATAKI
21) Dr. Zsuzsanna VIZI
22) Dr. Károly VÖRÖS
RESEARCH TOPIC:
1) Molecular level study of disease processes involved in chronic enteropathy in dogs, identification of diagnostic and therapeutic biomarkers, and examination of targeted therapeutic options. Occurrence and role of enteropathogenic Escherichia coli in gastrointestinal diseases of dogs. Research collaboration dr. With András Adorján (Department of Epidemiology and Microbiology)
2) Fecal microbiota transplantation. Method development and application in dogs.
3) Examination of the composition of early enteral nutrition in experimental and spontaneous pancreatitis animal models (dog). Comparison of serum amyloid-A and other acute phase proteins in acute pancreatitis in dogs.
4) Determination of serum and urinary hepcidin reference values in healthy dogs by ELISA and LC/MS-MS methods. The alterations of serum hepcidin concentrations in certain disease groups, primarily in non-regenerative anaemias caused by chronic diseases and in chronic liver diseases.
5) Digital sound processing in cardiology diagnostics. Clinical diagnosis and treatment of heartworm disease.
6) Transesophageal and transthoracic ultrasound-guided interventions in the treatment of congenital heart diseases and rhythm disorders in dogs.
7) Determination of the reference value of the urinary albumin/creatinine ratio in healthy dogs. Examine the importance of albuminuria and proteinuria in animals with kidney disease, particularly regarding its change in response to medical treatment.
8) Examination of the renal effect of Dirofilaria repens infection (blood, urine and histopathological abnormalities).
9) Answering technical and patient selection questions that arise during hemodialysis treatment and more precisely defining treatment indications.
10) Analysis of RNA-based cardiac biomarkers that can be measured from blood using molecular methods.
11) Identification of glucocorticoid receptor beta isoform in the dog.
12) The effect, long-term efficacy, safety and practical applicability of ex vivo boosted immune cell therapy (EBIC) in dogs with atopic dermatitis (cAD (canine atopic dermatitis)).
TOP PUBLICATIONS:
1) Kállai B.M., Csöndes J., Kiss G., Bodrogi L., Rónai Zs., Mészáros T.: Restrained expression of canine glucocorticoid receptor splice variants α and P prognosticates fatal disease outcome in SIRS; Scientific Reports, 11:24505, 2021.
2) Pan-European Study on the Prevalence of the Feline Leukaemia Virus Infection – Reported by the European Advisory Board on Cat Diseases (ABCD Europe).
Studer N, Lutz H, Saegerman C, Gönczi E, Meli ML, Boo G, Hartmann K, Hosie MJ, Moestl K, Tasker S, Belák S, Lloret A, Boucraut-Baralon C, Egberink HF, Pennisi MG, Truyen U, Frymus T, Thiry E, Marsilio F, Addie D, Hochleithner M, Tkalec F, Vizi Z, Brunetti A, Georgiev B, Ludwig-Begall LF, Tschuor F, Mooney CT, Eliasson C, Orro J, Johansen H, Juuti K, Krampl I, Kovalenko K, Šengaut J, Sobral C, Borska P, Kovaříková S, Hofmann-Lehmann R.
Viruses. 2019 Oct 29;11(11):993.
3) International collaborative study to assess cardiovascular risk and evaluate long-term health in cats with preclinical hypertrophic cardiomyopathy and apparently healthy cats: The REVEAL Study.
Fox PR, Keene BW, Lamb K, Schober KA, Chetboul V, Luis Fuentes V, Wess G, Payne JR, Hogan DF, Motsinger-Reif A, Häggström J, Trehiou-Sechi E, Fine-Ferreira DM, Nakamura RK, Lee PM, Singh MK, Ware WA, Abbott JA, Culshaw G, Riesen S, Borgarelli M, Lesser MB, Van Israël N, Côté E, Rush JE, Bulmer B, Santilli RA, Vollmar AC, Bossbaly MJ, Quick N, Bussadori C, Bright JM, Estrada AH, Ohad DG, Fernández-Del Palacio MJ, Lunney Brayley J, Schwartz DS, Bové CM, Gordon SG, Jung SW, Brambilla P, Moïse NS, Stauthammer CD, Stepien RL, Quintavalla C, Amberger C, Manczur F, Hung YW, Lobetti R, De Swarte M, Tamborini A, Mooney CT, Oyama MA, Komolov A, Fujii Y, Pariaut R, Uechi M, Tachika Ohara VY. J Vet Intern Med. 2018 May;32(3):930-943.
4) Effect of clinical signs, endocrinopathies, timing of surgery, hyperlipidemia, and hyperbilirubinemia on outcome in dogs with gallbladder mucocele.
Jaffey JA, Pavlick M, Webster CR, Moore GE, McDaniel KA, Blois SL, Brand EM, Reich CF, Motschenbacher L, Hostnik ET, Su D, Lidbury JA, Raab O, Carr SV, Mabry KE, Fox-Alvarez W, Townsend S, Palermo S, Nakazono Y, Ohno K, VanEerde E, Fieten H, Hulsman AH, Cooley-Lock K, Dunning M, Kisielewicz C, Zoia A, Caldin M, Conti-Patara A, Ross L, Mansfield C, Lynn O, Claus MA, Watson PJ, Swallow A, Yool DA, Gommeren K, Knops M, Ceplecha V, de Rooster H, Lobetti R, Dossin O, Jolivet F, Papazoglou LG, Pappalardo MCF, Manczur F, Dudás-Györki Z, O’Neill EJ, Martinez C, Gal A, Owen RL, Gunn E, Brown K, Harder LK, Griebsch C, Anfinsen KP, Gron TK, Marchetti V, Heilmann RM, Pazzi P, DeClue AE. Vet J. 2019 Sep;251:105350
5) Long-term incidence and risk of noncardiovascular and all-cause mortality in apparently healthy cats and cats with preclinical hypertrophic cardiomyopathy.
Fox PR, Keene BW, Lamb K, Schober KE, Chetboul V, Luis Fuentes V, Payne JR, Wess G, Hogan DF, Abbott JA, Häggström J, Culshaw G, Fine-Ferreira D, Cote E, Trehiou-Sechi E, Motsinger-Reif AA, Nakamura RK, Singh M, Ware WA, Riesen SC, Borgarelli M, Rush JE, Vollmar A, Lesser MB, Van Israel N, Lee PM, Bulmer B, Santilli R, Bossbaly MJ, Quick N, Bussadori C, Bright J, Estrada AH, Ohad DG, Del Palacio MJF, Brayley JL, Schwartz DS, Gordon SG, Jung S, Bove CM, Brambilla PG, Moïse NS, Stauthammer C, Quintavalla C, Manczur F, Stepien RL, Mooney C, Hung YW, Lobetti R, Tamborini A, Oyama MA, Komolov A, Fujii Y, Pariaut R, Uechi M, Yukie Tachika Ohara V. J Vet Intern Med. 2019 Nov;33(6):2572-2586.
GRANT PROJECTS:
1) Treatment of chronic intestinal diseases based on the RNA interference principle.
2) Development of species-specific infusion solutions