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Research Topics Effects of butyrate on enteral and hepatic microsomal drug-metabolizing cytochrome P450 (CYP) enzymes in chicken and rat

Effects of butyrate on enteral and hepatic microsomal drug-metabolizing cytochrome P450 (CYP) enzymes in chicken and rat

It is of special importance to examine the effects of the epigenetically active butyrate in intestinal and hepatic microsomal drug-metabolizing CYP enzymes. Beyond the hepatic drug-metabolizing system, intestinal CYPs are also highly involved in the biotransformation of xenobiotics taken up orally. Cooperation with the Department of Pharmacology and Toxicology (Dr. György Csikó).

Staff: Anna Kulcsár, Dr. Gábor Mátis, Dr. Zsuzsanna Neogrády