University of Veterinary Medicine Budapest

Course description

Histopathology (pathohistologia) is the study of the pathological changes in the organs by light and electron microscopy (EM) and it is an essential investigation method of pathology.

During histopathological practicals we can get acquainted with the nature of those diseases which have been seen in the pathological practicals and have been described in the lectures, such as the study of the nature of cells making up the inflammation, the activity of inflammatory cells (e.g.: phagocytosis, extravasation, cell proliferation etc.) and the study of the light microscopic signs of cell division and the accumulation and appearance of various substances (e.g.: fibrin, exudates, hyaline, calcium-salts etc.) during inflammatory processes.

Practical lessons theme

Group 1-2-3-4 will start on the István-street campus according to time table.

Week 1-2. – INTRODUCTION and GENERAL PATHOLOGY (feb. 11., 18.)

Basic of histopathology (sending sample, using microscope, checking slides)
Pathological simple and necrobiotic fatty infiltration
Skeletal muscle dystrophy caused by ionofor antibiotic toxicosis
Chronic demarcation
Tubercule (bo)

Week 3-4. – INFLAMMATIONS, TUMORS I. (feb. 25., mar. 3.)

INFLAMMATIONS

Diffuse purulent inflammation (phlegmone)
Hemorrhagic inflammation
Fibrinous (croupous) inflammation

TUMORS I.

Lymphoma
Benign mixed tumor of the mammary gland
Mastocytoma
Melanoma
Trichoblastoma

Week 5-6. – TUMORS II. (mar. 10., 17.)

MESENCHYMAL TUMORS

Fibroma
Fibrosarcoma
Sarcoma polymorphocellulare
Haemangioma cavernosum

EPITHELIAL TUMORS

Adenoma
Adenocarcinoma
Carcinoma planocellulare keratoides (squamous cell carcinoma)
Papilloma

Week 7-8. – LUNG, KIDNEY (mar. 24., 31.)

PNEUMONIAS

Serous-desquamative bronchopneumonia
Fibrinous (croupous) pneumonia
Pneumonia caused by Actinobacillus pleuropneumoniae
Interstitial pneumonia

KIDNEY

Etylen-glicol toxicosis
Subacute glomerulonephritis
Interstitial nephritis
Kidney fibrosis (end stage kidney)

Week 9. – SPRING HOLIDAY (apr. 7.)

Week 10-11. – LIVER, INTESTINES, BRAIN (apr. 14., 21.)

LIVER, INTESTINES

Cholangiohepatitis
Infectious canine hepatitis (Rubarth’s disease)
Liver cirrhosis
Paratuberculous enteritis
Enteritis caused by parvovirus

BRAIN

Acute leptomeningitis
West-Nile encephalitis
Encephalitis caused by Listeria monocytogenes

Week 12. – PRACTICAL EXAM I. (apr. 28.)

Week 13. – PRACTICAL EXAM II. (may 5.)

Week 14. – RETAKE EXAM (may 12.)

Evaluation description

Histopathology is part of the Special Pathology in 8th semester and separate part of the Pathology 3 final exam.

Exam information

The students have to recognize and diagnose in details one randomly chosen section from the topics of histopathology practicals. Simple recognition of the sections without being able to explain the observed lesions is not enough to pass the exam.
The Histopathology exam is organized separately from the oral part of the final exam, on a given day of the week (see above). If the knowledge of the student was not acceptable, the histopathology exam has to be repeated on the next histopathology exam date or before the other 2 parts on the same day with the rest of the final exam.

Week 12. – PRACTICAL EXAM I. (apr. 28.)

Week 13. – PRACTICAL EXAM II. (may 5.)

Week 14. – RETAKE EXAM (may 12.)